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You have 365 days to try Cellular Hydration Serum and see the results for yourself risk-free. If you are not 100% satisfied — simply contact us and we will gladly refund your money.


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$37.8 Per Jar

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By selecting "Subscribe & Save" option above, you agree to receive a shipment of Cellular Hydration Serum every 3 months. You are authorizing us to charge your credit card every 3 months, matching the package you have selected. Coupon or discount codes can only be applied to initial purchases and such discounts do not apply to future autoship products. You can stop shipments at any time in your customer account or by calling our customer support team toll free at (800) 595-0735, Mon - Sun 24/7, Outside the US, call us at +1-703-740-4444. All terms & conditions apply

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365 money back guarantee

You have 365 days to try Cellular Hydration Serum and see the results for yourself risk-free. If you are not 100% satisfied — simply contact us and we will gladly refund your money.


Real results from our customers who used Pureance


Noticed fewer fine lines & wrinkles in 3 weeks*

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Would recommend Pureance to their friends and family*

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Experienced better
hydration in 2 weeks*

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*Results based on feedback from a selected group of 14 individuals in a private continuous focus group. Results not typical, your may vary.

Get Cellular Level Hydration With The Deep Penetrating Power Of Tremella Mushroom

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  • More Hydrating power than hyaluronic acid for cellular level hydration
  • Contains protein, fiber, minerals, polysaccharides, vitamin D, and 18 other essential amino acids that help to rejuvenate tired looking skin
  • Block skin-discoloration by up to 59.7%, which results in brighter skin
  • Increased skin hydration for less dry, flaky skin
Trumella mushroom Trumella mushroom

The Cellular Hydration Serum... based on the power of the ancient Tremella Mushroom. It’s a potent natural hydrator that has been proven to be several times more hydrating than Hyaluronic Acid. Plus, Tremella has been shown in studies to block skin-discoloration melanin by up to 59.7%, which can result in brighter skin. And it’s great for damaged skin and acne scars as well. The result is better hydration, increased collagen production, and firmer, younger looking skin.

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Stimulate your skin’s natural collagen production and reduce fine lines and wrinkles

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Increase hydration levels for smooth, plump looking skin

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Boost antioxidant levels for radiant skin that looks decades younger

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We are so confident about the quality of our premium class skincare products that we offer extraordinary 365 day money back guarantee to every purchase.

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Our products are carefully formulated using only superior quality natural USDA Organic certified ingredients. Feel the outstanding skincare as nature intended to.

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We’re proud to be a PETA certified cruelty-free brand. Our products are not tested on animals in any stage of the process and they do not contain any animal based ingredients.


F.A.Q (Frequently Asked Questions) About Cellular Hydration Serum By Pureance

What does USDA Certified Organic CELLULAR HYDRATION SERUM by PUREANCE do for my skin?

Doctor-Approved CELLULAR HYDRATION SERUM by PUREANCE protects your skin to the deepest layers at the cellular level. Its organic botanicals are scientifically proven to nourish skin so your body can REPAIR, REBALANCE, and RESTORE a healthy, plump, silky, glowing, and glorious complexion. Its luxurious botanicals reduce wrinkles, repair rough, damaged, and irritated skin with incredible results! Studies show Tremella gets 5% BETTER results than Hyaluronic Acid!

What are the Effective Ingredients in CELLULAR HYDRATION SERUM by PUREANCE?

Ingredients: Aloe Barbadensis Leaf Juice* Tremella Fuciformis Extract*, Acer Pensylvanicum (Striped Maple) Leaf Extract*, Acer Saccharum (Sugar Maple) Leaf Extract*, Acer Rubrum (Red Maple) Leaf Extract*, Calendula Officinalis Flower Extract*, Hamamelis Virginiana (Witch Hazel) Extract*, Mushroom Extract*, Rosa Canina Seed Oil*, Glycerin*, Sodium Alginate, Citrus Aurantium Dulcis (Orange) Peel Oil*.

*Denoted organically produced ingredient.

What are the expected effects of each ingredient in CELLULAR HYDRATION SERUM by PUREANCE?

Maple Leaf Elastin & Antioxidant Youth Complex.

Acer Rubrum (Red Maple) leaf Extract – New research presented at the 256th National Meeting & Exposition of the American Chemical Society suggested that Maple Leaf extract could significantly protect against wrinkles. Their studies found that Glucitol-core Containing Gallotannins (GCGs) help protect your skin from immune markers and dark age spots. GCGs comprise galloyl groups that block the enzyme elastase from breaking down elastin proteins in the skin, leading to fine lines, wrinkles, folds, and sagging. That means you retain more elastin and a plump, youthful complexion!

Acer Saccharum (Sugar Maple) Leaf Extract – Researchers from the University of Rhode Island identified 68 gallotannins, 25 flavonoids, gallic acid, quinic acid, catechin, epicatechin, and 9 other gallic acid derivatives, providing exceptional antioxidant properties. Free radicals destroy the cell walls of your skin, making skin appear dull and damaged. Antioxidants combat aging skin. Natural Alpha Hydroxy Acids (AHA) acids, namely Malic and Tartaric and help slough off dull, dead skin cells, revealing fresh cells and improving skin’s appearance.

Acer Pensylvanicum (Striped Maple) Leaf Extract – Maple Leaf has immune-modulating properties beneficial for acne and balances the skin’s pH. These skin dynamos work together, improving connective tissue health. Maple Leaf protects the skin against premature aging caused by oxidative stress. It combats free radicals and increases skin elasticity, resulting in firmer, tighter skin, even skin tone, and a radiant glow!

Calendula Officinalis Flower Extract (Marigold) – Marigold has many active ingredients, including antioxidants, antibacterial, quercetin, alkaloids, flavonoids, saponins, terpenoids, and Vitamin E. Its potent anti-microbial and repairing properties are excellent for acne and breakouts. It may also protect your skin from the Sun’s UV rays. Marigold protects, soothes, calms, firms, and hydrates your skin!

Rosa Canina Seed Oil (Rosehip) – Potent anti-aging skin restorative! Rosehip's delicate oil nourishes your skin's deepest layers while it hydrates, moisturizes, exfoliates, and brightens. Naturally high in Vitamins A and C, it boosts collagen production, strengthening the skin’s infrastructure matrix and improving elasticity. Together with plumping cellular moisture, it’s fabulous at smoothing wrinkles, especially crow’s feet. It soothes reddened, angry areas. Leaves your healthy skin illuminating your face!

Aloe Barbadensis Leaf Juice – Aloe is your skin’s idol! Power-packed with skin-nourishing Vitamins A, B1, B2, B3, B5, B6, B12, C, E, Choline, and Folic Acid. It soothes skin with superior calming properties and is excellent for repairing damaged skin. Aloe’s aloin blocks up to 30% of the Sun’s ultraviolet rays. It shields against DNA and cellular damage caused by harmful substances. Aloe’s potent enzymes rejuvenate aged tissue, penetrating up to 7 layers deep. It stimulates collagen production, strengthening your skin’s matrix, significantly improving skin elasticity, and reducing wrinkles. It plumps your skin by increasing moisture retention. Aloe helps repair, protect, strengthen, giving you a giant push toward your dream complexion!

Tremella Fuciformis Extract – Goodbye Hyaluronic Acid, hello Organic Tremella! Hyaluronic Acid (HA) can hold up to 1000 times its weight in moisture; Organic Tremella holds about 5% more. Tremella’s smaller molecules easily penetrate deeper skin layers, dramatically plumping fine lines and wrinkles. Tremella is a protein-rich mushroom with potent antioxidant properties. It stimulates cell growth, accelerating skin rejuvenation. It lightens under-eye dark circles, repairs, and smooths. It nourishes skin with nutrients, including 18 essential amino acids. It improves elasticity and firms your skin. It inhibits skin-discoloring melanin by up to 59.7%, resulting in a brighter skin complexion. Its high Vitamin D content helps repair damaged skin cells, especially acne scars. Tremella is an organic Superstar!

Hamamelis Virginiana (Witch Hazel) Extract – This blissful tonic helps calm irritations and soothes sensitive skin! Witch Hazel acts like an astringent, helping shrink your pores and fight acne-causing bacteria. It reduces reddened skin (erythema), caused by injury or irritation, by up to 27% It improves dry or damaged skin, reduces flaking, and restores the suppleness for youthful-looking skin!

Glycerin – A magnet for moisture! Glycerin helps reduce oily skin, won’t clog your pores, and hydrates your skin by attracting moisture. It alleviates dry, cracked skin. One study concluded Glycerin hydrates the outer layer of skin, improves skin cell metabolism, protects barrier function, shields from irritants, and accelerates cellular repair. Hydrates and inspires healthy skin like nothing else!

Sodium Alginate – Silky smooth skin! Alginate comes from a nutrient-rich brown alga called Phaeophycota. This polysaccharide gel hydrates and soothes, leaving your complexion silky soft. It has potent combat abilities in fighting free radicals and bacteria. Alginate leaves your skin healthy and radiant!

Citrus Aurantium Dulcis (Orange) Peel Oil – Skin-lightening champion! Rich in Hesperidin flavonoids and Vitamin C, it has potent antioxidant properties and reduces irritations. And it fights bacteria and lightens skin tone. Studies show Hesperidin offers skin protection against UVA-induced damage of fibroblasts and collagen. Citrus oil helps make your skin glow!


Botanicals are Nature’s nourishment as well as medicine for your skin. Hyaluronic Acid (HA) is famous for its water-trapping abilities, but it doesn’t penetrate beyond the surface. Tremella mushrooms hold 5% more moisture and easily penetrates deeper layers, dramatically plumping up fine lines and wrinkles. And Tremella is good for sensitive and problem skin types unlike HA. Aloe is overflowing with skin nourishment to kickstart healthy skin repair and regeneration. And we’re just getting started in the benefits to your skin…

The botanicals in Doctor-Approved CELLULAR HYDRATION SERUM by PUREANCE are scientifically proven to help:

  • Nourish your skin at the cellular level
  • Stimulate collagen production, boosting elasticity for a tighter, firmer complexion
  • Strengthen skin infrastructure matrix for resilient skin
  • Accelerate repairs of damaged skin cells
  • Protect DNA from cellular damage
  • Neutralize fight free radicals
  • Calm irritated, reddened, angry areas
  • Soothe acne and breakouts
  • Reduce scars, including burns
  • Block UVA and UVB rays up to 30%
  • Shrink pores without clogging or causing blackheads
  • Reduce under-eye dark circles
  • Exfoliate dead skin cells
  • Alleviate dry, flaky, cracked, and rough skin
  • Protect against harmful elements, bacteria, and germs and detoxifies
  • Absorb & Trap moisture
  • Balance oily skin
  • Plump out fine lines and wrinkles
  • Lighten skin to an even healthy glow
  • Soften skin to a supple, radiant, clear, silky-smooth radiance
  • Gentle and hypoallergenic for all skin types
  • USDA Certified Organic


CELLULAR HYDRATION SERUM is perfect for MEN & WOMEN who are fed up with signs of premature aging. It nourishes and hydrates to the deepest layers, strengthening the collagen matrix, stimulating elasticity and firmness, plumps wrinkles, and repairs damaged skin. CELLULAR HYDRATION SERUM is the ultimate in USDA Certified Organic Skincare!


YES! In fact, we recommend daily use, morning, and night, to protect your skin from continued exposure to environmental stressors and deliver consistent nourishment for robust skin repair and regeneration to help keep you young-looking for decades to come.

Are there any side effects for CELLULAR HYDRATION SERUM by PUREANCE?

All the ingredients are natural and USDA Certified Organic. Although there are no reports of side effects, some extracts are sourced from flowers and may cause allergies in sensitive people.

Sensitivity Testing: Apply a dime-sized amount on your inner elbow and wait 24 hours. If there’s no reaction – you’re good to go!


We recommend using CELLULAR HYDRATION SERUM in the morning and evening. Cleanse your face with a natural glycerin soap (that doesn’t dry or deposit harsh chemicals) or another natural, gentle cleanser and pat dry.

Place a dime-sized amount of CELLULAR HYDRATION SERUM on your third fingertip and gently apply an even layer to your face and neck. Don’t rub, as this pulls and stretches your skin. The third fingertip is the weakest using minimum pressure force and is the recommended etiquette for skincare.

How can I order CELLULAR HYDRATION SERUM right now?

Click the button on this page, and it’ll take you to a secure order page where you can make your desired selection.

CELLULAR HYDRATION SERUM’s superior quality, potent USDA Certified Organic formulation is only $49 per jar.

SAVE MORE when you STOCK UP with our exclusive 2 or 3 jar discount packages.

Your investment could drop to our rock-bottom $42 per month for a 3-jar supply, which works out to just $1.40 per day.

Will I be able to track my order once it has been placed?

ABSOLUTELY! Feel at ease knowing you can track your order at any time. Once we process your order, you’ll get an email with your confirmation details. If you have any questions, please email us or call our experts 24-7 for assistance. Toll-free at (800) 595-0735, anytime! Outside the US, call us at +1-703-740-4444.

What are you waiting for?

Turn back the hands of time and reclaim your confidence and giddy youthful spirit! Click the button on this page and get your Organic CELLULAR HYDRATION SERUM by PUREANCE today!

Remember, when placing your order today, you’ll receive your 365-Day Love it or Your Money Back Guarantee!

Safety Facts: We recommend that you consult your doctor before using any product if you have any pre-existing chronic skin conditions.

Cellular Hydration Serum

Cellular Hydration Serum

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Dr. Sarah Jensen graduated from Saint Louis University School of Medicine and the Learnskin Integrative Dermatology Certificate Course. She has been a practicing dermatologist for 20 years and is dual-board certified. She is an avid believer in the breadth of medicine from allopathic to naturopathic to Traditional Chinese to Ayurvedic medicine.

Dr. Sarah Jensen Dr. Sarah Jensen Dr. Sarah Jensen